As Rob Reiner concisely put it,

there are 2 main world issues now:
1. climate change
2. the survival of democracy/democracies.

In the States, adhering to rule of law has become the current issue with steps being taken by Democrats of the Dept. of Justice to hold the guilty responsible for the Jan. 6 insurrection. Law and order must be maintained. Justice must be doled out. Trump and his supporters must be held to account.

Also, voting rights are on the line (relative to democracy), and the only path forward may be to get rid of the filibuster before the midterms.